While this disease affects one third of the world’s population, some scientists suggest that a new technology called gene drive could be a game-changer.

Gene Drives – manipulating the DNA of mosquitoes to pass down an extinction gene

The research consortium Target Malaria, mostly funded by the Bill & Melinda Gates Foundation and the Open Philanthropy Fund, is developing genetically engineered mosquitoes in the lab that would either make all offspring male or all female offspring infertile. They use the Crispr-Cas methodology to implant a system into their DNA that would replicate when mosquitoes mate, ensuring that this gene spreads throughout the wild mosquito population. But while some hope that this would be the magic bullet to suppress mosquitoe populations and stop the malaria transmission cycle, this currently unproven high risk technology poses fundamental questions for humanity: How far are we willing to go, how high can the risks and uncertainties be in order to test a hypothesis?

The Risks of Gene Drive mosquitoes